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肖海滨 Haibin Xiao

博士

专业:分析化学

简介:
博士,山东理工大学化学化工学院讲师,硕士研究生导师。

个人介绍

      肖海滨,山东淄博人,博士,讲师,硕士研究生导师。2017年12月获山东师范大学分析化学专业博士学位,2018年1月进入山东理工大学化学化工学院工作。主要从事活细胞及活体内活性氧及微环境的荧光检测研究。目前,在国内外高水平学术期刊发表论文20篇,其中以第一或通讯作者在 Coordin. Chem. Rev., Angew. Chem. Int. Ed., Chem. Sci. 等期刊发表论文13篇。获2019年山东省自然科学奖二等奖(第四位)。
 
主要论文:
(1) Haibin Xiao*, Ping Li* and Bo Tang. Recent progresses in fluorescent probes for detection of polarity. Coordin. Chem. Rev., Accepted.
(2) Haibin Xiao#, Wen Zhang#, Ping Li*, Wei Zhang, Xin Wang and Bo Tang*. Versatile fluorescent probes for imaging the superoxide anion in living cells and in vivo. Angew. Chem. Int. Ed., 2020, 59, 4216-4230.
(3) Haibin Xiao*, Tian Zhang, Yaqi Dong, Xiaojuan Song, Lingbao Xing, Jin Zhou, Yuying Liu and Shuping Zhuo*, The photophysical properties and imaging application of a new polarity-sensitive fluorescent probe, Analyst, Accepted, Doi: https://doi.org/10.1039/D0AN01064B.
(4) Yaqi Dong, Haibin Xiao*, Lingbao Xing, Chuanchen Wu, Jin Zhou, Ziyan Zhou,Yuying Liu*, Shuping Zhuo and Ping Li*. Two-photon fluorescence visualization of lysosomal pH changes during mitophagy and cell apoptosis. Talanta, 2020, 209, 120549.
(5) Haibin Xiao, Yaqi Dong, Jin Zhou, Ziyan Zhou, Xiaozhong Wu, Rongzhou Wang, Zhichao Miao, Yuying Liu* and Shuping Zhuo*. Monitoring mitochondrial pH with a hemicyanine-based ratiometric fluorescent probe. Analyst, 2019, 144, 3422-3427.
(6) Haibin Xiao#, Ruilin Zhang#,Chuanchen Wu, Ping Li*, Wen Zhang* and Bo Tang. A new pH-sensitive fluorescent probe for visualization of endoplasmic reticulum acidification during stress. Sensor. Actuat. B-Chem., 2018, 273, 1754-1761.
(7) Haibin Xiao, Chuanchen Wu, Ping Li* and Bo Tang*. Simultaneous fluorescence visualization of endoplasmic reticulum superoxide anion and polarity in myocardial cells and tissue. Anal. Chem., 2018, 90, 6081-6088.
(8) Haibin Xiao, Chuanchen Wu, Ping Li*, Wen Gao, Wen Zhang, Wei Zhang, Lili Tong and Bo Tang*. Ratiometric photoacoustic imaging of endoplasmic reticulum polarity in injured liver tissues of diabetic mice. Chem. Sci., 2017, 8, 7025-7030.
(9) Haibin Xiao, Xiao Liu, Chuanchen Wu, Yaohuan Wu, Ping Li*, Xiaomeng Guo and Bo Tang*. A new endoplasmic reticulum-targeted two-photon fluorescent probe for imaging of superoxide anion in diabetic mice. Biosens. Bioelectron., 2017, 91, 449-455.
(10) 肖海滨, 李平*, 张雯, 张卫, 唐波*. 有机分子荧光探针成像检测线粒体内ROS的研究进展,中国科学: 化学, 2017, 47, 955-972.
(11) Haibin Xiao, Ping Li*, Shan Zhang, Wei Zhang, Wen Zhang and Bo Tang*. Simultaneous fluorescence visualization of mitochondrial hydrogen peroxide and zinc ions in live cells and in vivo. Chem. Commun., 2016, 52, 12741-12744.
(12) Haibin Xiao, Ping Li, Xiufen Hu, Xiaohui Shi, Wen Zhang and Bo Tang*. Simultaneous fluorescence imaging of hydrogen peroxide in mitochondria and endoplasmic reticulum during apoptosis. Chem. Sci., 2016, 7, 6153-6159.
(13) Haibin Xiao#, Ping Li#, Wei Zhang and Bo Tang*. An ultrasensitive near-infrared ratiometric fluorescent probe for imaging mitochondrial polarity in live cells and in vivo. Chem. Sci., 2016, 7, 1588-1593.
 
授权发明专利:
(1)唐波,李平,肖海滨,一种对环境极性敏感的近红外荧光探针及其合成方法和应用,2015.4.30,中国,ZL201510218987.9
(2)唐波,李平,肖海滨,张雯,具有大斯托克斯位移的近红外荧光染料及合成方法与应用,2014.10.31,中国,ZL201410606444.X
 
承担项目:
(1)国家自然科学基金青年项目,21907058,糖尿病诱导肝损伤模型中活性氧物种的荧光/光声双模态成像研究,2020/01-2022/12,26万元,在研,主持。
(2)山东理工大学博士启动基金,细胞及活体内过氧化氢的荧光/光声双模态成像,2018,主持,10万。